Stock futures inched up in the premarket hours of Thursday as investors digested the Federal Reserve’s first rate cut since December, lowering its benchmark by 25 bps to 4.00%–4.25%.
Here are some of Thursday’s biggest stock movers:
Biggest stock gainers
- Nanobiotix (NASDAQ:NBTX) +64% – Shares advanced after releasing new Phase 1 data showing its therapy JNJ-1900 (NBTXR3), combined with immune checkpoint inhibitors, achieved a 47.4% objective response rate and 78.9% disease control rate in heavily pretreated primary cutaneous melanoma patients resistant to anti-PD-1 therapy. The treatment, which showed a favorable safety profile and a median overall survival of 14.6 months, established a recommended Phase 2 dose at 33% of tumor volume. Investigators said the early efficacy signals warrant further trials as a potential new option for this difficult-to-treat population.
- IonQ (NYSE:IONQ) +7% – Shares jumped after the quantum computing firm signed an MoU with the U.S. Department of Energy to support its Quantum in Space initiative, including an orbital demo of quantum-secure communications via IonQ’s satellite platform. The partnership will also explore quantum networking, sensing, navigation, and time synchronization, with DOE officials highlighting its potential to create a “quantum sandbox” in space for future resource exploration and advanced manufacturing.
Biggest stock losers
- Cracker Barrel Old Country Store (NASDAQ:CBRL) -9% – Shares slid after mixed FQ4 results showed weaker sales and 25% profit erosion, with FY2026 sales guidance of $3.35B–$3.45B missing the $3.52B consensus. The outlook assumes a 4%–7% decline in traffic, overshadowing better-than-expected comparable sales. The company guided adjusted EBITDA to $150M–$190M and capex to $135M–$150M, while also approving a $0.25/share dividend (payable Nov. 12) and a $100M buyback program.
- Red Cat Holdings (NASDAQ:RCAT) -7% – Shares fell after the drone technology company announced an underwritten public offering of common stock, with proceeds earmarked for working capital, operating costs, and its new unmanned surface vessel division. Underwriters may also get a 30-day option to purchase up to 15% additional shares.
- Nucor (NYSE:NUE) -4% – Shares slipped after the steelmaker guided Q3 EPS to $2.05–$2.15, well below the consensus of $2.56. The company flagged declines across all three operating segments, citing lower volumes, margin compression, higher costs, and weaker scrap processing profits. The company repurchased 0.7M shares at an average $140.46 in Q3 and will report results on Oct. 27.