Stock futures were higher Monday morning while Treasury yields slipped as investors awaited September’s upcoming nonfarm payrolls report, hoping for clarity on U.S. labor market health, while also weighing the potential impact of a looming U.S. government shutdown.
Here are some of Monday’s biggest stock movers:
Biggest stock gainers
- Enanta Pharmaceuticals (NASDAQ:ENTA) +23% – Shares jumped ahead of a company’s scheduled conference call Monday at 8:30 a.m. ET to disclose mid-stage trial data for its RSV antiviral candidate, zelicapavir.
- GSK (NYSE:GSK) +3% – Shares rose following the announcement that CEO Emma Walmsley will step down after nine years in the role and be succeeded by Chief Commercial Officer Luke Miels, effective Jan. 1. Walmsley said 2026 will be “a pivotal year for GSK to define its path for the decade ahead,” making it the right time for new leadership.
Biggest stock losers
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MoonLake Immunotherapeutics (NASDAQ:MLTX) -83% – Shares plunged after late-stage trial results for its hidradenitis suppurativa drug Sonelokimab fell far short of expectations, with analysts slashing ratings and price targets. RBC downgraded the stock to sector perform from outperform (PT cut to $10 from $67), citing data that cast “meaningful doubt” on the drug’s future potential, while Stifel lowered it to hold from buy (PT $13 from $77), saying results were “significantly worse than we or the Street anticipated” and warning the regulatory path ahead remains uncertain.