Stock futures edged down during Monday’s premarket session as market participants reacted to President Donald Trump’s announcement of a new $100,000 fee for H-1B visa applications, effective September 21, 2025.
Here are some of Monday’s biggest stock movers:
Biggest stock gainers
- Metsera (NASDAQ:MTSR) +46% – Shares surged after reports that Pfizer (PFE) is nearing a $7.3B takeover of the weight-loss drug maker. The deal would value Metsera at $47.50 per share in cash, plus an additional $22.50 contingent on performance milestones, according to the Financial Times. The offer represents a ~42% premium to Friday’s close. An announcement could come as early as Monday, pending final deal talks.
Biggest stock losers
- Kenvue (NYSE:KVUE) -3% – Shares slipped following a report that the Trump administration plans to announce a potential link between Tylenol (acetaminophen) use during pregnancy and autism. Tylenol is a core product of Kenvue’s McNeil Consumer Healthcare unit. Despite the White House’s confirmation of an impending announcement on autism, Kenvue reaffirmed that no proven causal link exists between acetaminophen and autism.
- Bitcoin USD (BTC-USD) -2% – Cryptocurrency-exposed stocks slipped about 3% to 4% in Monday’s premarket session, pressured by the fallout from over $1.5B in bullish bets being liquidated in the digital asset market. The wave of forced unwindings in leveraged crypto positions dragged sentiment lower, prompting early weakness in names like Coinbase (NASDAQ:COIN), Marathon Digital (NASDAQ:MARA), Strategy (NASDAQ:MSTR), Bitfarms (NASDAQ:BITF), HIVE Digital Technologies (NASDAQ:HIVE), and Riot Platforms (NASDAQ:RIOT).