Lilly makes over $1.9B bet on autoimmune diseases in pact with Repertoire

  • Privately owned Repertoire Immune Medicines announced a partnership worth up to $1.9B with Eli Lilly (LLY) on Thursday to develop and commercialize a new class of treatments targeting autoimmune diseases.
  • According to the Cambridge, MA-based company, the collaboration focuses on developing tolerizing therapies designed to restore immune homeostasis and create a durable remission, unlike currently available therapies, which are associated with generalized immune suppression.
  • As part of the deal, Repertoire will be responsible for early development efforts until candidate nomination. Lilly (LLY) will take over clinical development, production, regulatory activities, and potential commercialization.
  • In exchange, the Indiana-based pharma giant will pay $85M upfront to Repertoire in addition to tiered royalties on net sales, as well as development and commercial milestones worth up to $1.84B.

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