More people staying on a GLP-1 for weight loss after one year

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  • The percentage of people on a GLP-1 weight loss medication such as Novo Nordisk’s (NVO) Wegovy (semaglutide) or Eli Lilly’s (NYSE:LLY) Zepbound (tirzepatide) sticking with treatment after a year is on the rise.
  • For individuals who started treatment in Q1 2024, 63% of people were still using a GLP-1 a year later, according to data from pharmacy benefit manager Prime Therapeutics. For those who started on a GLP-1 in 2021, the figure was just 33% a year later.
  • Prime attributed the boost in staying on therapy to the resolution of shortages of both drugs in 2024.
  • However, long-term use of GLP-1s continues to be an issue. Many users of the medications stop using them, often citing side effects as an issue.
  • Prime’s data found that only 8% of individuals with obesity without diabetes who started on a GLP-1 were still taking the treatment at three years.

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