Summary:
- Cassava Sciences’ stock has declined significantly since its peak, with ongoing skepticism about the efficacy of its Alzheimer’s drug, simufilam.
- Phase 3 trial results for simufilam are anticipated by year-end, which could either validate or disprove its effectiveness.
- Cassava has faced legal and scientific scrutiny, with key figures resigning and the company settling a $40m SEC penalty.
- The new CEO remains cautiously optimistic but acknowledges the potential for ambiguous results and the need for further FDA consultations.

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Investment Thesis
Cassava Sciences (NASDAQ:SAVA) reported its Q3 earnings today, Thursday Nov. 7. Nearly four years ago to the day, Cassava stock traded >$90 per share, and there was genuine hope that its lead product, simufilam, an oral pill with almost no side effects, could not only
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